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Nitric Oxide Supplement
Transdermal Formula

A nitric oxide supplement transdermal formula is a great addition to complement any oral formulas you may be taking for this purpose. 

TESTIMONIAL for Nitric Oxide Delight lotion:

"I did try the lotion.  It definitely imparts a slight healthy tan color (probably thanks to the Pycnogenol®).  It also has a pleasant “natural earthy woody” smell.  I don’t know if it’s psychological, but I think there’s a “tingle” feel to it as well.  It’s very good!"

- Joel Melillo


I designed this proprietary formula after extensive experimentation with the key active ingredients. This consisted of trying varying amounts of each compound individually to ascertain its particular effects. Then I tried a variety of combinations to see what the synergistic effects would feel like. With a 40 year background of training in body awareness, both my husband and I spent the better part of a year comparing notes. The resulting formula is now available exclusively from Peak Health Now.

INGREDIENTS LIST: Purified water, Glycine, Carthamus tinctorius (Safflower) seed oil, Sepigel 305 (Polyacrimide, C13-14 isoparaffin, laureth-7), L-Proline, Pycnogenol®, Methylsolfonylmethane (MSM), Oak Wood Extract, Chrysin, Prunus Americana (Apricot kernel oil), Vitis vinifera (Grape) seed oil, Cannabis sativa (hemp) seed oil, Gingko Biloba, Tocopherol (Vitamin E) oil, Xanthan gum, Sodium gluconate, Potassium sorbate, Sorbic acid

Below, the benefits of each of the active ingredients are described. 


Nitric Oxide Supplement
Transdermal Ingredients:
PYCNOGENOL®

Pycnogenol® benefits are among the most well-researched among nutritional compounds. 

IMPORTANT: Pycnogenol® benefits can ONLY be obtained from French Maritime Pine Bark Extract from Horphag Research! **Beware of products that contain 'grapeseed extract' or other compounds and claim it to be the same - they are lying.**

My personal experience of this compound is remarkable. Shortly after my first 50 milligram dose taken orally, I felt a mild flush - a bit like a niacin flush, only more subtle. Gradually I increased my daily dosage to over 200 milligrams and began noticing a lovely tingle of increased circulation all through my body to my very fingertips and toes - even hours away from taking it. 

I was so impressed with the effects of Pycnogenol® oral use, that I became intrigued to obtain the 100% pure powdered extract and explore its use as a skin application.

NOTE: Except where noted, benefits described below have only been scientifically proven with oral use. However, my extensive personal experience with transdermal (skin applicacion) of the pure extract powder suggests there is still more to be learned about transdermal application of Pycnogenol®.

PROVEN BENEFITS OF PYCNOGENOL® APPLIED TRANSDERMALLY (TO THE SKIN)

Improved skin health and collagen renewal

Antioxidant potency

Anti-microbial activity

anti-inflammatory activity

Accelerates wound healing and lowers scar formation

Effective for treating acne

Anti-photoaging and sun protection

Excellent circulation is one of the cornerstones of health. 

Because of its significant support of endothelial function (endothelial cells line all our blood vessels and when healthy, produce Nitric Oxide and regulate blood flow), Pycnogenol® pine bark extract can contribute to a heightened sense of well-being.

As we age, our microcirculation (capillary circulation) decreases. Slowly, capillaries get blocked by coagulated blood cells, and tissues fed by the capillaries are subject to 'micro-strokes' - lack of blood supply resulting in cell death. Part of aging is this cell death happening more and more. Aging is gradual death on a microscopic level.

Since every cell in every organ and body tissue needs abundant vascular support to be fed, cleansed and healthy, decrease in capillary integrity equals getting old!

Pycnogenol benefits to circulatory health are many and documented by reputable research.

Collagen elasticity and tissue strength are supported by Pycnogenol. It follows that it supports the strength of blood vessels, valves, heart and all tissues of the circulatory system.

The anti-aging support provided by genuine French Maritime Pine Bark Extract would be important if the above was all it did - but there is MUCH more!

PYCNOGENOL BENEFITS LIST

1 - Pycnogenol® genuine French Maritime Pine Bark Extract is taken from pines in a relatively pristine area away from pesticides and other environmental toxins.

IMPORTANT: There are many products on the market that claim to be Pycnogenol; they are NOT.

2 - NO toxic solvents are used in obtaining the extract.

3 - Research shows that Pycnogenol is effective for controlling platelet activity and preventing blood clots - yet does not pose the danger that aspirin does of increasing bleeding time.

4 - This is a super-antioxidant - helps ALL other antioxidants to persist longer in the body.

5 - Pycnogenol binds to collagen elastin to keep our tissues strong.

6 - Helps us better utilize Vitamin E and Vitamin C.

7 - Decreases oxidative stress.

PYCNOGENOL BENEFITS CIRCULATORY FUNCTION

Improves endothelial function (endothelium is the layer of cells lining the blood vessels). 

With improved endothelial function we get:

More Nitric Oxide production. Nitric Oxide (NO) is a vasodilator which means it relaxes blood vessels so they open and more blood gets to every organ and tissue in your body, supporting better health. NO is well-known to support better erectile potency in men and sexual response in women.

Improved endothelial function means a healthy circulatory system and helps prevent arterial narrowing. Nitric Oxide is anti-inflammatory - therefore keeps blood vessel walls strong and flexible.

Healthy endothelial function also directs blood flow where it is most needed - for example to the muscles during exercise.


Nitric Oxide Supplement
Transdermal Ingredients:
OAK WOOD EXTRACT

French Oak Wood Extract is obtained by water extraction, the safest, most environmentally friendly method. Roburins and other flavinoids only found in oak wood can be helpful for chronic fatigue. Elagitannins in oak wood are metabolized to ellagic acid, whic is then converted into urolitins - proven to be present in our bodies. 'Recent research...has shown  preliminary evidence of the anti-inflammatory, anti-carcinogenic, anti-oxidant and anti-microbial effects of urolithins...'  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679724/  Oak Wood Extract is also good for people who simply want more energy.

Because this compound has not been researched with regard to transdermal use, I was asked by the company of origin to use the generic description. However, I can assure you that this Oak Wood Extract is the finest in the world.

NOTE: On our first batch of product, it was mistakenly printed on label as Oak Bark Extract (my mistake) and will be corrected on subsequent batches.


Nitric Oxide Supplement
Transdermal Ingredients:
PURE L-PROLINE

PURE L-PROLINE 

RECOMMENDED TO ENHANCE STRUCTURE & FUNCTION RELATING TO NUTRITIONAL NEEDS AND DEFICIENCIES PERTAINING TO: 

  • Functioning as a precursor to hydroxyproline 
  • Production of collagen, cartilage and connective tissue
  • Joint and tendon health
  • Tissue repair and wound healing 
  • Maintenance of healthy skin and prevention of aging in skin tissue 
  • Supporting DNA synthesis

WHAT IS PROLINE? 

Proline is an amino acid found primarily in meat, and synthesized in the body from Glutamate in the tricarboxylic acid cycle, and Ornithine in the urea cycle. It is the precursor to hydroxyproline, which is essential in collagen production. This is necessary for tissue repair and wound healing. It is also important for joint and tendon health as well as strengthening the heart muscle. Collagen is also a component of skin. Proline improves skin tissue as well as helping to prevent loss of collagen, which happens in the aging process. Proline also stimulates DNA and protein synthesis, and especially hepatic protein synthesis. 

PROLINE AND SKIN 

Skin is the largest organ of the body, and Proline and Hydroxyproline make collagen, which is a component of skin tissue. Younger skin is thicker and has more elasticity than older skin. Aged skin is thinner and the decrease in collagen creates changes including less fibrous and elastic elements. Older skin is less subtle and smooth. Aging, combined with the effects of sun and free radical damage, results in older looking, wrinkled skin. Proline, along with other amino acids such as Glycine, help create new cell formation and can contribute to maintaining younger looking skin. Lubrication is also important, such as drinking sufficient water and including essential fatty acids in the diet. Montiff Super EFA Plus with borage oil, rich in essential fatty acids, can have beneficial results on the texture and health of skin. 

PROLINE AND JOINT HEALTH 

Proline is the amino acid necessary for the production of collagen and cartilage for healthy joints, ligaments and tendons. Joints are complicated structures that connect bones to allow for movement. There are different types of joints, including hinge, ball-and-socket, saddle and pivot joints. They are bound on the outside by fibrous bands, called ligaments. Each ligament contains fibrous tissue of collagen, in a capsule, which surrounds the joint. The lining of the capsule is a thin membrane called the synovium that continuously produces a small amount of fluid for lubrication. Cartilage is a smooth, flexible tissue that covers the surface where the bones meet, and acts as a shock absorber and reduces friction. Osteoarthritis, is caused by wear and tear on the joints, as well as possible free radical damage, and generally is associated with aging. While heredity and obesity effect the incidence of Osteoarthritis, it may also develop due to overuse or injury to the joints. The articular cartilage, which is the smooth lining of the joint, begins to deteriorate, and may eventually expose the bone. Without sufficient cartilage, movement of the joint becomes restricted and painful. Swelling, stiffness and pain are symptoms of this often-debilitating condition, which affects the joints of the hips, knees, and spine. L-Proline is included in Montiff Joint-Eez to assist with collagen and cartilage repair; however additional Proline may be indicated for severely damaged joints. 

Proline is an amino acid that is essential for the production of collagen and cartilage and is necessary for healthy skin, joints and tendons. 

Each capsule of Pure L-Proline contains 500 mg. of the highest quality L-Proline. 

ADDITITIONAL PROPERTIES OF PROLINE 

  • Proline is necessary to support DNA and protein synthesis, and low levels may impair proper protein synthesis. 
  • Low Proline levels can lead to a decrease in the number of hepatic polyribosomes. 
  • Proline is important for wound healing, and decreases in protein synthesis have been noted in burn and traumatized patients. 
  • Decreases in serum Proline levels have been noted in prolonged endurance runners and others following prolonged exercise.

    REFERENCES:
  • Cynober, Luc (edited by), Amino Acid Metabolism and Therapy in Health & Nutritional Disease, 1995.
  • Di Pasquale, M, Amino Acids and Proteins for the Athlete, the Anabolic Edge, 1997.
  • Latifi, Rifat, M.D., Amino Acids in Critical Care and Cancer, 1994.
  • Jaksi,T., Wagner, D.A., and Young, V.R. “Proline Metabolism in Adult Male Burn Patients and Healthy Control Subjects”, Am. J.
    Clinical Nutrition, 1991.
  • Huq F., Thompson M, Ruell, P., “Changes in Serum Amino Acid Concentrations During Prolonged Endurance Running, J. Physiol.,
    1993.
  • Hiramatsu, T., Cortiell, J., Marchini, J.S. Chapman, T., Young, V.R., “ Plasma Protein and Leucine Kinetics: Response to 4 Weeks
    With Proline-Free Diets in Young Adults”, Am. J. Clinical Nutrition, 1994.
  • Balch, J. M.D., Balch, P., C.N.C., Prescription for Nutritional Healing, 1997.
    Copyright 6/2000© 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease 


Nitric Oxide Supplement
Transdermal Ingredients:
PURE L-GLYCINE

PURE L-GLYCINE 

Glycine is involved with gluconeogenesis and is necessary for proper glucose balance, collagen formation and for healthy central nervous function. 

Each capsule of Pure Glycine contains 500 mg. of pure, highest quality Glycine. 

WHAT IS GLYCINE? 

  • Promoting Gluconeogenesis
  • Formulation of collagen, found in skin and connective tissue.
  • Promoting synthesis of creatine to help prevent degeneration of muscle tissue and
    may have an effect on Muscular Dystrophy and other degenerative muscular
    disorders.
  • Central nervous system by functioning as an inhibitory neurotransmitter and may
    have an effect on Epilepsy.
  • Improper metabolism involved in non-Ketotic Hyperglycemia
  • Participating in the synthesis of purines, porphyrins, and glyoxylic acid
  • Prostate health
  • Involved in bile acid metabolism and gastrointestinal function.

Glycine is a non-essential amino acid synthesized in the body through various complex pathways involving Threonine, Serine, Hydroxyproline and Choline metabolism. It is involved in the synthesis of purines, porphyrins, creatine and glyoxylic acid, and is also a biochemical constituent of the tripeptide glutathione. Glycine is also essential for the synthesis of bile and nucleic acids, and it is used in many commercial gastric antacid preparations. It is important in the central nervous system where it acts as one of the main inhibitory neurotransmitters. Although high amounts of Proline and 4-hydroxyproline are found in collagen (important for skin and connective tissue), almost 1/3 rd is comprised of Glycine. High amounts of Glycine are found in gelatin, which is a denatured collagen. Low plasma levels of Glycine are noted in hypoglycemics, those with viral infections and fevers, CFS (Chronic Fatigue Syndrome) and anemia. A metabolic disorder causing excessive levels of Glycine in the spinal fluid is responsible for Non-Ketotic Hyperglycemia, or Rett Syndrome, which has symptoms of autism. 

GLYCINE AND GLUCONEOGENESIS 

Glycine is considered a glucogenic amino acid, which includes others such as Glutamine, Alanine, Threonine, Serine, Methionine, Tyrosine, and Lysine, and thus is involved in maintaining blood sugar levels. Hypoglycemics are low in Glycine and supplementation with Glycine, along with other glucogenic amino acids, is beneficial in regulating low blood sugar levels, and increasing energy in those who are lethargic due to this condition. 

GLYCINE AND NEUROLOGICAL EFFECTS 

Glycine is one of the main precursors to inhibitory neurotransmitters, along with Taurine, GABA, and other such as Tyrosine, Phenylalanine, Serine and Threonine. 

  • SCHIZOPHRENIA
    Research regarding supplementation with Glycine, along with traditional medications (antipsychotics), appear to have beneficial results with Schizophrenics, although less effective when combined with clozapine.
  • GLYCINE AND MEMORY AND ATTENTION
    Because of its receptor sites, Glycine appears to be beneficial in memory. In a double- blind crossover study, both young and middle-aged men significantly benefited with improved episodic memory. It was suggested that supplementation with Glycine could significantly improve memory that may be impaired due to jet lag, disrupted sleep, or work fatigue, and be helpful in memory retrieval problems associated with schizophrenia, Parkinson’s disease and Huntington’s disease.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease 

 

GLYCINE AND ANTICARCINOGENIC PROPERTIES 

In a preliminary study over a 55-week period (published in 1999), Glycine was administered to animals with hepatic cancer. The results indicated that Glycine prevented the formation of small tumors by 23%, inhibited the development of medium tumors by 64% and prevented the formation of the largest tumors by nearly 80%. The study conclusion was that Glycine might be an effective chemoprotective agent. In another study published in1999 with animals with melanomas, those fed with Glycine had 50-70% less tumor size than the control group. This study concluded that dietary Glycine prevents tumor growth in vivo by inhibiting angiogenesis via the inhibition of endothelial cell proliferation. 

GLYCINE AND GROWTH HORMONE LEVELS 

Studies have indicated significant increase in growth hormone levels on those who were administered between 4-12 grams of Glycine. 

OTHER BENEFITS OF GLYCINE 

  • Increases creatine synthesis. Glycine, along with Arginine supplementation, increases endogenous creatine synthesis.
  • Acute ischaemic stroke. A study of patients administered 1-2 grams of Glycine sublingually, within 6 hours after the onset of acute ischaemic stroke in the carotid artery, indicated favorable clinical effects. 
  • REFERENCES
  • Di Pasquale, M, Amino Acids and Proteins for the Athlete, the Anabolic Edge, 1997.
  • Cynober, Luc (edited by), Amino Acid Metabolism and Therapy in Health & Nutritional Disease, 1995.
  • Balch, J. M.D., Balch, P., C.N.C., Prescription for Nutritional Healing, 1997.
  • Gusev, Skvortsova et al., “Neuroprotective Effects of Glycine for Therapy of Acute Ischaemic Stroke”, Cerebrovasc Dis., Jan.-Feb.2000.
  • Rose, Cattley, Dunn, wong et al, Univ. of N. Carolina, “Dietary Glycine Prevent the Develop. Of Liver Tumors Caused by the Peroxisome
    Proliferator WY-14, 643”, Carcinogenesis, Nov. 1999.
  • Rose, Madren et al, U. of N. Carolina, “ Dietary Glycine Inhibits the Growth of B 16 Melanoma Tumors in Mice”, Carcinogenesis, May
    1999.
  • Kasai, Kobayashi, Shimoda, “Stimulatory Effect of Glycine on Human Growth Hormone Secretion”, Metabolism, 1978.
  • Banay-Schwartz, Palkovitis, Lajtha, “ A Heterogeneous Distribution of Functionally Important Acids in Brain Areas of Adult and Aging
    Humans”. Neurochem. Res., 1993.
  • Evins, Fitzgerald, Wine, Rosselli, Goff, Mass. Gen. Hospital , “Placebo-Controlled Trial of Glycine to Clozapine in Schizophrenia”, Am. J.
    Psychiatry, May 2000.
    Copyright 7 2000©

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease 


Nitric Oxide Supplement
Transdermal Ingredients:
CHRYSIN

Chrysin is a naturally occurring flavanoid compound extracted from passiflora incarnate (passion flower).

Chrysin and Testosterone

This compound has a host of health benefits; among them, helping prevent Testosterone from being converted into estrogens. It is known to be an aromatase inhibitor (aromatase in excess can convert Testosterone to Estrogen - a bad idea for both men and women). Inhibiting excess aromatase back down to healthier levels helps our energy and sex drive benefit from the Testosterone our bodies produce.

Low Testosterone in both men and women can cause fatigue, depression, low libido, poor sexual function, thinning skin, blood sugar imbalances and cardiovascular problems among other problems. This can tend to happen more as we go through our middle years.

Chrysin is very poorly absorbed into the bloodstream when taken orally - oral use has virtually NO effect on aromatase! Part of the reason for this is that Chrysin is NOT water soluble, therefore harder to absorb through the digestive tract.

Using Chrysin Cream, 100 mg per day is much MORE effective than taking 1 - 3 GRAMS orally!

Chrysin is HIGHLY absorbable when used as a transdermal (skin) application. Transdermal use is the effective way to absorb and utilize this beneficial compound.

Chrysin prevents conversion of Testosterone to Estrogen (more powerful in effect than most anti-aromatase drugs). In the 1980's Chrysin was discovered to inhibit aromatase, an enzyme which converts Testosterone into estrogens (Kellis JT Jr et al 1984). 

Chrysin Transdermal Cream for Beautiful Skin

Chrysin is used for skin conditioning, anti-inflammatory actions and antioxidant qualities. Research strongly indicates that the way this flavinoid works is by inhibiting PGE-2 formation and COX-2 expression. This also attests to its ability to quench excessive free radical activity.

Lab testing indicates that Chrysin may have benefits to skin. Chrysin is said to activate an enzyme - Uridine Diphosphate-Glucaronosyltransgerase - also known as UGT1A1. This enzyme helps to eliminate iron deposits and bilirubin pigmentation (dark areas) such as dark circles under eyes.

Because this flavinoid is well-researched to provide anti-inflammatory benefits, it may help eliminate puffiness around eyes and face, as well.


Nitric Oxide Supplement
Transdermal Ingredients:
GINGKO BILOBA

Over 120 clinical trials have been done on Gingko Biloba, the majority of which examined its effects on cognition in elderly people with impaired cognitive function. Terpene lactones in Gingko extract are potent inhibitors of a platelet-activating factor. This reduces platelet aggregation (stickiness), promoting improved blood circulation, which in turn increases delivery of oxygen and glucose to body tissues.

Gingko Biloba can increase endothelium-derived relaxing factor (Nitric Oxide), relaxing blood vessels for increased circulatory volume.

Gingko Biloba contanis active compounds that protect circulatory and nervous systems. They include terpinoids, and flavinoids such as proanthocyanidins, rutin, quercetin and kaempferol. Flavinoids are strong antioxidants and scavenge free radicals. This protects cells against oxidative damage. Flavinoids also strengthen capillaries and protect mitochondria of cells.


Nitric Oxide Supplement
Transdermal Ingredients:
MSM (Methylsolfonylmethane)

MSM is an organic sulfur compound. It is vital for collagen production, helping prevent weak sagging, dry, cracked skin.

MSM can help improve collagen formation, leading to smoother skin.

MSM increases flexibility in all tissues - including skin, joints, muscle.

MSM provides the organic sulfur needed for normalizing collagen formation, improving healthy, strong hair and nails. Sulfur also is important for detoxifying heavy metals abd other toxins.

It also increases body's ability to detox, and to recover from injury. It has anti-inflammatory properties as well.


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Throughout this website, statements are made pertaining to the properties and/or functions of food and/or nutritional products. These statements have not been evaluated by the FDA and these materials and products are not intended to diagnose, treat, cure or prevent any disease. For all health and medical questions, please consult with your doctor. By viewing this site, you are stating that you agree with this disclaimer.


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Chrysin Extract (Passiflora Incarnata) in transdermal form. 

Supports integrity of Testosterone in the body.

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