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Vas-Cu-Care:
Montiff's Superbly Formulated Supplement for Endothelial Health!

Vas-Cu-Care is more effective than just Arginine alone! 

Ingredients in this formula increase nitric oxide production with just the right proportions of L-Arginine HCL, L-Citrulline and full-spectrum nutrient support for endothelial system (lining of all blood vessels).

Cardiovascular health and integrity of the endothelium (lining of all your blood vessels) is essential for healthy circulation, as well as erectile potency in men and sexual responsiveness in women.  

Did you know that nitric oxide production is vital for cardiovascular health and sexual response? 

Nitric oxide is a vasodilator as well - increasing your circulatory capacity for increased health and pleasure in life.

That nitric oxide rush sure feels good - just ask my clients! Vas-Cu-Care is part of their regular self-care program (and mine as well)!

How to Make Sure the Supplements You Buy are Fresh, Potent and Effective! (new window)

Vas-Cu-Care Information

Note: The information below, except where noted is the official company description of this product.

Vas-Cu-Care™ is a blend of amino acids, vitamins, minerals, and antioxidants that support the endothelial system of the body for artery, vein, and capillary health.

Vas-cu-Care Ingredients

Supplement Facts: Serving Size: 4 capsules / Servings per container: 30

Amount Per Serving: Vitamin C (ascorbic acid) 240 mg, Vitamin E (d-a tocopheryl succinate) 300 IU, Vitamin B6 (pyridoxal 5 phosphate) 40 mg, Folic acid 800 mcg, Vitamin B12 (cyanocobalamin) 400 mcg, Magnesium (magnesium oxide) 12 mg, Selenium (L-selenomethionine) 60 mcg, Chromium (chromium polynicotinate) 40 mcg, Potassium (potassium aspartate) 20 mg

Proprietary Blend 2068 mg: (L-arginine HCl, L-citruline, L-carnitine fumarate, taurine, quercetin), Pine Bark extract 40 mg, Alpha lipoic acid 20 mg, Blueberry fruit extract 20 mg

Other Ingredients: Cellulose, magnesium stearate, silicon dioxide.

RECOMMENDED FOR:

Heart support 

Prevention of damage to the heart from free radicals 

Reducing and prohibiting homocysteine, which can lead to heart attacks and strokes 

Those with existing coronary problems 

Those who want to improve their cardiac health 

Supporting the vascular system and helping to increase blood flow 

Those experiencing vascular problems 

Individuals who have a family history of vascular disease 

Helping to manage hypertension 

Supporting the endothelial system 

Helping to manage Atherosclerosis by assisting in the production of Nitric Oxide. 

WHAT IS NITRIC OXIDE AND ITS RELATIONSHIP TO ARGININE? 

Nitric Oxide (NO), a small molecule synthesized from Arginine in the body, is the endothelial relaxing factor (EDRF). It plays an essential role in the regulation of vascular homeostasis. 

In the cardiovascular system, Nitric Oxide’s important functions are for the modulation of cardiac contractility, regulation of vascular tone, and the prevention of vessel injury and Atherosclerosis. It is also an important free radical scavenger. 

Studies at major universities, as well as studies funded by the National Heart, Lung, and Blood Institute support the importance of Nitric Oxide, its role in the endothelial-vascular system of the body, and its relationship to Arginine supplementation. 

A study “Effect of L-Arginine on Plasminogen-Activator Inhibitor in Hypertensive Patients with Hypercholesterolemia” in “The New England Journal of Medicine”, Jan. 28, 1993 by Korbut, PhD., Bieron, M.D. and Gryglewski, M.D. discussed patients with high blood pressure and high cholesterol who were administered IV Arginine HCL. The infusion of L-Arginine was associated with a decrease in the plasma PAI and cholesterol levels as well as normalization of blood pressure in the hypertensive patients with hypercholesterolemia. 

WHAT IS THE ENDOTHELIAL SYSTEM AND WHAT IS THE IMPORTANCE OF ARGININE?

The endothelial cells are critical to healthy arterial/venal function. They surround the smooth muscle rings and expand the artery’s diameter, affecting the blood carrying capacity.

They originate on the outside of the artery and weave through the walls 

These cells, like human cells, require oxygen and nutrients, and Arginine is essential for their proper function. 

Endothelial cells make Nitric Oxide (NO) from Arginine, which is responsible for the endothelial relaxing factor (EDRF), and plays an essential role in the regulation of vascular homeostasis. 

In the cardiovascular system, Nitric Oxide’s important functions are for the modulation of cardiac contractility, regulation of vascular tone, and the prevention of vessel injury and atherosclerosis. It is also an important free radical scavenger. 

Recent studies suggest that damage from hypertension, high cholesterol, and other coronary heart disease factors impairs the ability of the endothelium to produce necessary Nitric Oxide. 

WHAT ARE SOME OF THE OTHER BENEFITS OF VAS-CU-CARE™? 

The highest quality amino acids and other nutraceuticals are used in VAS-CU-CARE™, as well as all other Montiff products. Desiccant pads are included to ensure freshness. This product is enclosed in a vegetarian encapsulation. 

L-CITRULLINE enhances the production of Arginine in the kidneys, thus helping to increase Nitric Oxide interaction and conversion of L-Arginine. 

L-CARNITINE is an amino acid, synthesized in the human liver and found in red meat (not found in vegetable forms of protein). Carnitine is important in maintaining a healthy cardio-vascular system and is essential for fat metabolism, increasing HDL levels, and reducing triglycerides. High levels of carnitine are found in the heart muscles and function to supply the heart with the metabolic energy necessary to pump. It can protect the heart from myocardial ischemia and benefit people who suffer from angina pectoris. 

Carnitine improves arrhythmias, prevents congestive heart failure, may prevent myocardial necrosis, and helps improve the recovery rate of those with myocardial infarctions. Supplementation of carnitine has been shown to improve walking capacity of those suffering from pain caused by blockage in the major arteries (or intermittent claudication). 

L-Carnitine Fumarate is an active form of carnitine, for increased bioavailability. 

HOW DO ANTIOXIDANTS PROTECT AGAINST HEART & VASCULAR PROBLEMS? 

Free radicals are oxygenated molecules that enter the body from food, water, and air and occur from biochemical processes from within. They attack and damage tissue in the heart and throughout the body. They also oxidize lipids, increasing LDL cholesterol and the chance of atherosclerosis. Antioxidants act as inhibitors of lipoprotein oxidation and thus reduce the risk of cardiovascular disease, as well as protect the cardiac cells from their harmful effects 

ANTIOXIDANTS IN VAS-CU-CARE™ ARE: 

VITAMIN E: Is especially important in cardiac health and numerous studies in major universities support the benefits of Vitamin E for prevention of heart attacks, reducing serum cholesterol, as well as for vascular health. 

Vitamin E has an effect on prostaglandins. Medical research has noted the important anti-platelet aggregation properties of Vitamin E and its influence in vascular disease. Thus, it helps to prevent blood clots and is often used in conjunction with aspirin to help decrease the incidence of heart attacks and strokes. 

ALPHA LIPOIC ACID: One of the most powerful antioxidants, alpha lipoic acid increases Glutathione levels in the cells, and enhances the activity of other antioxidants, especially E and C. 

ALA provides antioxidant protection against LDL’s, helping to prevent fatty deposits on arterial walls. Ischemia-reperfusion injuries, which occur in conditions such as stroke, cardiac arrest, and head trauma result from the release of free radicals during reoxygenation of tissue that has become hypoxic. Since ALA is efficacious in preventing ischemia-reperfusion injuries, it may be important to patients who have strokes, cardiac infarction, and open-heart surgery. 

SELENOMETHIONINE: (Chelated Mineral Compound): Methionine, an amino acid, aids in the maintenance of Glutathione pools. Combining it with selenium enhances its bioavailability. Methionine disorders are associated with the presence of homocysteine, which is correlated with heart attacks and strokes. Folic acid is also very important for the prevention of excessive homocysteine as well as other B vitamins necessary for proper metabolism. 

TAURINE: An amino acid found in meat and absent in vegetarian diets, has several functions, including the regulation of the potassium-sodium-calcium-magnesium flux for proper heart muscle function. It is also an antioxidant and potentiates vitamin E activity. 

POTASSIUM: A mineral critical for heart cell metabolism. 

BLUEBERRY EXTRACT: Rich in antioxidant and anti-inflammatory properties, blueberry extract contains high amounts of flavonoids, polyphenes, and anthocyanins. Researchers at the USDA Human Nutrition Center (HNRCA) studied blueberries and found that they had the highest antioxidant capacity when compared to 40 other fresh fruits and vegetables.  

Vas-Cu-Care 120 caps - Ingredients and Directions for Use: 

**This item is not available for shipment to Canada.**

Supplement Facts: Serving Size: 4 capsules / Servings per container: 30 

Amount Per Serving: Vitamin C (ascorbic acid) 240 mg, Vitamin E (d-a tocopheryl succinate) 300 IU, Vitamin B6 (pyridoxal 5 phosphate) 40 mg, Folic acid 800 mcg, Vitamin B12 (cyanocobalamin) 400 mcg, Magnesium (magnesium oxide) 12 mg, Selenium (L-selenomethionine) 60 mcg, Chromium (chromium polynicotinate) 40 mcg, Potassium (potassium aspartate) 20 mg 

Proprietary Blend 2068 mg:  (L-arginine HCl, L-citruline, L-carnitine fumarate, taurine, quercetin), Pine Bark extract 40 mg, Alpha lipoic acid 20 mg, Blueberry fruit extract 20 mg 

Other Ingredients: Cellulose, magnesium stearate, silicon dioxide. 

Directions:

As a dietary supplement, take two to three capsules daily, or as recommended by a health care professional. Contains necessary amino acids, vitamins, minerals, and anti-oxidants for maximum results. 

Note from Ellen Landauer: In using this product, my clients and I find that 1) It seems to work best taken during the night with water or fruit juice on an empty stomach 2) After working up to full dose over 5 or 6 days, if you have a large build (over 175 lb) you might try adding an extra capsule to the recommended dose for a total of 4 - and see how you feel. Adjust dose to what feels best to you.**

Do not refrigerate. 

Keep out of reach of children. 

Store in a cool, dry place. 

Contains no starch, corn, milk, wheat, yeast, sugar, eggs, salt, artificial colors, binders, flavors, preservatives, fish derivatives or Meat products.

**Research References at bottom of page.**

Vas-cu-Care is the PREMIER formula for nitric oxide benefits to the endothelium (blood vessel lining). 

2000 mg of a proprietary blend of L-Arginine HCL, L-Citrulline, L-Carnitine fumarate, Taurine and Quercetin, plus vitamins, minerals and antioxidants assure comprehensive cardiovascular support.

Vas-cu-Care 120 caps - Nitric Oxide/ Endothelial formula / 1 - 3

Peak Nitric Oxide Packages for You:
Vas-cu-Care Combined With Synergistic Formulas
takes the NO experience to a new level!

________________________________________________

REFERENCES:

Fried, Robert, PhD., and Merrill, Woodson, M.D., The Arginine Solution, 1999 

Panza, Julio A, M.D., and Cannon III, Richard O., M.D. edited by, Endothelium, Nitric Oxide, and Atherosclerosis, 1999. 

Cynober, Luc A. edited by, Amino Acid Metabolism and Therapy in Health and Nutritional Disease, 1995 

Korbut, R., PhD., Bieron, Krzysztof, Bieron, M.D., Gryglewski, 

M.D.,D.Sc.,N.Copernicus Univ. School of Med,. “Effect of L-Arginine on Plasminogen-Activator Inhibitor in Hypertensive Patients with Hypercholesterolemia”, “New England J. of Med., Jan. 1993. 

Furchgott RF., “The Discovery of Endothelium-Derived Relaxing Factor and its Importance in the Identification of Nitric Oxide”, J. Am Med. Assoc. 1996. 

Chowienczyk, P.J., Watts, G.F., Cockcroft, J.R., Ritter, J.M., “Impaired Endothelium-Dependent Vasodilatation of Forearm Resistance Vessels in Hypercholesterolemia”, “The Lancet”, 1992. 

Paulson, D.J. et al, The Carnitine System, A New Therapeutical Approach to Cardiovascular Diseases, 1995. 

Crayhon, Robert, M.S., The Carnitine Miracle, 1993. 

Panza, Julio A, M.D., and Cannon III, Richard O., M.D. edited by, Endothelium, Nitric Oxide, and Atherosclerosis, 1999. 

Basu, T.K., Temple, N.J., Garg, M.L. edited by, Antioxidants in Human Health and Disease, 1999. 

Rimm EB, Willett WC, Hu FB, Sampson L, Colditx GA, Manson JE, Hennekens C, Stampfer MJ: “Folate and Vitamin B^ from Diet and Supplements in Relation to Risk of Coronary Heart Disease Among Women”, JAMA 1998. 

McCully KS. Editorial: “Homocysteine, Folate, Vitamin B^, and Cardiovascular Disease, JAMA, 1998. 

Diaz MN, Frie B, Vita JA, Keaney JF: “Antioxidants and Astherosclerotic Heart Disease”, New England J. Med., 1998. 

Perry KJ, Refusum H, Morris RW, Ebrahim SB, Useland PM, Sharper AG., “Prospective Study of Serum Total Homocysteine Concentration and Risk of Stroke in Middle-Aged British Men”, Lancet 1995. 

Welch, GN, Loscalzo J, Review: “Homocysteine and Atherothrombosis”, New England J. of Med., 1998. 

Rimm, Eric B. et al., “Vitamin E Consumption and the Risk of Coronary Heart Disease in Men”, NEWJM, 1993. 

Morrison HI, Schaubel D, Desmeules M, Wigle DT, “Serum Folate and Risk of Fatal Coronary Heart Disease”, JAMA, 1996. 

Cynober, Luc A. edited by, Amino Acid Metabolism and Therapy in Health and Nutritional Disease, 1995. 

Basu, T.K., Temple, N.J., Garg, M.L. edited by, Antioxidants in Human Health and Disease, 1999. 

Packer, Lester, PhD., Colman, Carol, The Antioxidant Miracle, 1999. 

Bell, Gocheaur, “Characteriza of Coronary Arterial Reactiv. Of Berry Anthocyanins”. Presented at Experimental Biology 2002. 

Robbers, Tyler, Tyler’s Herbs of Choice: The Therapeutic Use of Phytomedicinals, Haworth Press 1999. 

Krupa, D., “Berry, Berry, Berry-Good”, American Physiology Society (APS) 2004. 

Amees, Shigenaga, Hagan, “Oxidants, Antioxidants, & the Degenerative Diseases of Aging”, Proc., Nat Sci USA, 1993. 

Prior, RL et al. Journal of Agriculture Food Chemistry, #46, 1997. 

Howell, Nicholl, New England Journal of Medicine, #339, 1998. 

Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 1997. 

Teichert J, Kern J, Tritschler HJ, Ulrich H, Preiss R. Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers. Int J Clin Pharmacol Ther. 1998. 

Jacob S, Ruus P, Hermann R, Tritschler HJ, Maerker E, Renn W, Augustin HJ, Dietze GJ, Rett K. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic Biol Med. 1999. 

Packer L, Rimbach G, Virgili F. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med. 1999. 

Hayashi, Toshio. Packiasamy A.R. Juliet et. al. L-Citrulline and L-Arginine Supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits. PNAS September 20, 2005. vol. 102. 

Flam, Brenda R. Hartmann, Paul J. et. al., Caveolar Localization of Arginine Regeneration Enzymes, Argininosuccinate Synthase, and Lyase, with Endothelial Nitric Oxide Synthase., NITRIC OXIDE: Biology and Chemistry., vol. 5. pp 187-197. 2001. 

*These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.

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